Will Antidepressants Show Up On A Drug Test?

If you have depression and are taking a prescription medication like Prozac, you might worry that it could show up on a drug test. This is especially a concern if you must take a pre-employment drug screen for a new job. Because antidepressants are not considered drugs of abuse, they are not included in common urine drug screens.

How does Antidepressants affect a drug test?

The tests aren’t “altered” by the use of antidepressants, but if you list them and show a legitimate amount during the test, it would be viewed as “prescribed.” You are more likely to fail the test for not disclosing you use them (if asked) than you would be if they showed up as “legitimate” in your lab reports.

Can you take antidepressants on an employment drug screen?

If you are in treatment for depression, the good news is that antidepressants are not the drugs that an employer is looking for in an employment drug screen. The lab would have to do specific additional tests to look for antidepressants. The types of substances tested for on a typical employment drug screens include:

Can you get a false positive for antidepressants?

As antidepressants are not considered as drugs of abuse, your employer and labs have no reason to test you for them. But, your meds might cause false positive for illegal substances and get you into trouble because of similarity of the chemical structure.

Can a prescription drug show up on a drug test?

These tests aren’t sensitive enough to tell the difference between a prescription and a similar target drug. For instance, Wellbutrin, Prozac, the Trazadone drug class Desyrel, Serzone, and other tricyclic antidepressants trigger positive results for amphetamines.

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